| Date | Location | Result | |
| May 27, 2022 | Denver, CO | Texas Tyler 12, Southern Indiana 5 | Box score |
| May 26, 2022 | Denver, CO | Rogers State 7, Southern Indiana 2 | Box score |
| May 20, 2022 | Evansville, IN | Southern Indiana 3, Grand Valley State 2 | Box score |
| May 19, 2022 | Evansville, IN | Southern Indiana 2, Grand Valley State 1 | Box score |
| May 14, 2022 | Evansville, IN | Southern Indiana 7, Saginaw Valley 2 | Box score |
| May 14, 2022 | Evansville, IN | Southern Indiana 5, Saginaw Valley 0 | Box score |
| May 13, 2022 | Evansville, IN | Southern Indiana 9, Drury 3 | Box score |
| May 13, 2022 | Evansville, IN | Southern Indiana 10, Lindenwood 1 | Box score |
| May 12, 2022 | Evansville, IN | Saginaw Valley 1, Southern Indiana 0 | Box score |
| May 08, 2022 | East Peoria, IL | Southern Indiana 1, Indianapolis 0 | Box score |
| May 08, 2022 | East Peoria, IL | Southern Indiana 4, Lindenwood 1 | Box score |
| May 07, 2022 | East Peoria, IL | Southern Indiana 9, Maryville 5 | Box score |
| 5/1/2022 | St. Charles, Mo. | Southern Indiana 7, Lindenwood 1 | Box score |
| 5/1/2022 | St. Charles, Mo. | Southern Indiana 2, Lindenwood 0 | Box score |
| Apr 30, 2022 | St. Louis, Mo. | Southern Indiana 5, Missouri-St. Louis 0 | Box score |
| Apr 30, 2022 | St. Louis, Mo. | Southern Indiana 4, Missouri-St. Louis 1 | Box score |
| Apr 24, 2022 | Evansville, In | Southern Indiana 6, Missouri S&T 0 | Box score |
| Apr 24, 2022 | Evansville, IN | Southern Indiana 10, Missouri S&T 2 | Box score |
| Apr 23, 2022 | Evansville, IN | Southern Indiana 5, Maryville 3 | Box score |
| Apr 23, 2022 | Evansville, IN | Southern Indiana 5, Maryville 1 | Box score |
| Apr 16, 2022 | Evansville, IN | Southern Indiana 2, McKendree 1 | Box score |
| Apr 16, 2022 | Evansville, IN | McKendree 3, Southern Indiana 1 | Box score |
| 4/15/2022 | Indianapolis, Ind. | Southern Indiana 4, Indianapolis 3 | Box score |
| 4/15/2022 | Indianapolis, Ind. | Indianapolis 4, Southern Indiana 3 | Box score |
| Apr 10, 2022 | Bolivar, Mo | Southern Indiana 11, Southwest Baptist 0 | Box score |
| Apr 10, 2022 | Bolivar, Mo | Southern Indiana 8, Southwest Baptist 5 | Box score |
| 4/9/2022 | Springfield, Mo. | Southern Indiana 2, Drury 0 | Box score |
| 4/9/2022 | Springfield, Mo. | Southern Indiana 2, Drury 1 | Box score |
| Apr 03, 2022 | Evansville, IN | Southern Indiana 5, William Jewell 0 | Box score |
| Apr 03, 2022 | Evansville, IN | Southern Indiana 7, William Jewell 1 | Box score |
| Apr 02, 2022 | Evansville, IN | Southern Indiana 3, Rockhurst 2 | Box score |
| Apr 02, 2022 | Evansville, IN | Southern Indiana 5, Rockhurst 4 | Box score |
| Mar 27, 2022 | Quincy, IL | Southern Indiana 5, Quincy 3 | Box score |
| Mar 27, 2022 | Quincy, IL | Southern Indiana 8, Quincy 0 | Box score |
| 3/26/2022 | Kirksville, MO | Southern Indiana 11, Truman State 2 | Box score |
| 3/26/2022 | Kirksville, MO | Southern Indiana 16, Truman State 2 | Box score |
| Mar 21, 2022 | Evansville, IN | Southern Indiana 8, Illinois Springfield 0 | Box score |
| Mar 21, 2022 | Evansville, IN | Southern Indiana 6, Illinois Springfield 5 | Box score |
| Mar 20, 2022 | Evansville, IN | Southern Indiana 2, Lewis 1 | Box score |
| Mar 20, 2022 | Evansville, IN | Southern Indiana 1, Lewis 0 | Box score |
| Mar 08, 2022 | Winter Haven, FL | Southern Indiana 7, Ashland 1 | Box score |
| Mar 07, 2022 | Winter Haven, FL | Southern Indiana 8, Lynn 0 | Box score |
| Mar 05, 2022 | Winter Haven, FL | Minn. State-Mankato 2, Southern Indiana 0 | Box score |
| Mar 05, 2022 | Winter Haven, FL | Winona State 4, Southern Indiana 3 | Box score |
| Mar 04, 2022 | Winter Haven, FL | Southern Indiana 6, Central Missouri 2 | Box score |
| Mar 04, 2022 | Winter Haven, FL | Southern Indiana 3, St. Cloud State 2 | Box score |
| Feb 27, 2022 | Owensboro, KY | Ashland 10, Southern Indiana 3 | Box score |
| Feb 27, 2022 | Owensboro, KY | Northwood (MI) 5, Southern Indiana 4 | Box score |
| Feb 26, 2022 | Owensboro KY | Southern Indiana 7, Notre Dame (OH) 3 | Box score |
| Feb 26, 2022 | Owensboro, KY | Southern Indiana 10, Ohio Dominican 2 | Box score |
| Feb 20, 2022 | Smyrna, TN | Southern Indiana 10, Parkside 2 | Box score |
| Feb 20, 2022 | Smyrna, TN | Southern Indiana 8, Ferris State 3 | Box score |
| Feb 19, 2022 | Smyrna, TN | Southern Indiana 5, Findlay 1 | Box score |
| Feb 19, 2022 | Smyrna, TN | Southern Indiana 8, Kentucky Wesleyan 0 | Box score |
| Feb 18, 2022 | Smyrna, TN | Trevecca Nazarene 10, Southern Indiana 3 | Box score |
| Feb 18, 2022 | Smyrna, TN | Southern Indiana 13, Tiffin 5 | Box score |
| Feb 13, 2022 | Albertville, AL | Southern Indiana 10, Shorter 2 | Box score |
| Feb 13, 2022 | Albertville, AL | Mississippi College 14, Southern Indiana 4 | Box score |
| Feb 12, 2022 | Albertville, AL | Southern Indiana 16, Christian Brothers 13 | Box score |
| Feb 12, 2022 | Albertville, AL | Alabama-Huntsville 5, Southern Indiana 4 | Box score |
| Feb 11, 2022 | Albertville, AL | Southern Indiana 9, Carson-Newman 3 | Box score |
| Feb 11, 2022 | Albertville, AL | Delta State 2, Southern Indiana 1 | Box score |