| Date | Location | Result | |
| 02/28/16 | Rensselaer, IN (Scharf Fieldhouse) | Saint Joseph's (IN) 71, Southern Indiana 59 | Box score |
| 02/25/16 | Evansville, IN (PAC) | Bellarmine 87, Southern Indiana 59 | Box score |
| 02/20/16 | Statham Center - Lebanon, IL | Southern Indiana 53, McKendree 50 | Box score |
| 02/18/16 | Springfield, IL (TRAC) | Southern Indiana 77, Illinois Springfield 75 (OT) | Box score |
| 02/13/16 | Evansville, IN (PAC) | Southern Indiana 76, Missouri-St. Louis 69 | Box score |
| 02/11/16 | Evansville, IN (PAC) | Southern Indiana 74, Maryville 61 | Box score |
| 02/06/16 | Rolla, MO (Billy Key Court) | Missouri S&T 76, Southern Indiana 69 | Box score |
| 02/04/16 | Springfield, MO (O'Reilly Event Center) | Drury 70, Southern Indiana 56 | Box score |
| 01/30/16 | Evansville, IN (PAC) | Saint Joseph's 67, Southern Indiana 64 (OT) | Box score |
| 01/28/16 | Evansville, IN (PAC) | Indianapolis 73, Southern Indiana 64 | Box score |
| 01/23/16 | Somers, WI (DeSimone Gymnasium) | UW-Parkside 72, Southern Indiana 60 | Box score |
| 01/21/16 | Romeoville, IL (Neil Carey Arena) | Lewis 76, Southern Indiana 47 | Box score |
| 01/18/16 | Louisville, KY (Knights Hall) | Bellarmine 65, Southern Indiana 61 | Box score |
| 01/16/16 | Evansville, IN (PAC) | Truman State 60, Southern Indiana 42 | Box score |
| 01/14/16 | Evansville, IN (PAC) | Quincy 78, Southern Indiana 65 | Box score |
| 01/09/16 | Liberty, MO (Mabee Center) | William Jewell 68, Southern Indiana 65 | Box score |
| 01/07/16 | Kansas City, MO (Mason-Halpin FH) | Southern Indiana 68, Rockhurst 54 | Box score |
| 12/20/15 | Louisville, KY (Knights Hall) | Southern Indiana 66, Ferris State 48 | Box score |
| 12/19/15 | Louisville, KY (Knights Hall) | Southern Indiana 63, Northern Michigan 43 | Box score |
| 12/08/15 | Evansville, IN (PAC) | Southern Indiana 87, Salem Internatonal 55 | Box score |
| 12/05/15 | Evansville, IN (PAC) | Southern Indiana 79, Illinois Springfield 64 | Box score |
| 12/03/15 | Evansville, IN (PAC) | Southern Indiana 58, McKendree 45 | Box score |
| 11/29/15 | Evansville, IN (PAC) | Southern Indiana 71, West Virginia State 65 | Box score |
| 11/24/15 | Evansville, IN (PAC) | Southern Indiana 82, Alice Lloyd 45 | Box score |
| 11/21/15 | Ashland, OH (Kates Gymnasium) | Ashland 92, Southern Indiana 64 | Box score |
| 11/17/15 | Evansville, IN (PAC) | Southern Indiana 81, Midway 37 | Box score |
| 11/10/15 | Huntsville, AL | Southern Indiana 77, Alabama Huntsville 46 | Box score |