| Date | Location | Result | |
| 03/09/18 | Kates Gymnasium - Ashland, Ohio | Lewis 72, Southern Indiana 64 | Box score |
| 03/04/18 | Edwardsville, IL (Vadalabene Center) | Drury 62, Southern Indiana 52 | Box score |
| 03/03/18 | Edwardsville, IL (Vadalabene Center) | Southern Indiana 76, Lewis 68 | Box score |
| 03/01/18 | Edwardsville, IL (Vadalabene Center) | Southern Indiana 64, William Jewell 54 | Box score |
| 02/24/18 | Romeoville, IL (Neil Carey Arena) | Lewis 72, Southern Indiana 71 | Box score |
| 02/22/18 | Somers, WI (DeSimone Gymnasium) | Southern Indiana 75, UW-Parkside 53 | Box score |
| 02/17/18 | Kansas City, MO (Mason-Halpin FH) | Southern Indiana 81, Rockhurst 72 | Box score |
| 02/15/18 | Liberty, MO (Mabee Center) | Southern Indiana 67, William Jewell 54 | Box score |
| 02/10/18 | Evansville, IN (PAC) | Southern Indiana 68, Bellarmine 59 | Box score |
| 02/08/18 | Springfield, IL | Southern Indiana 64, Illinois Springfield 51 | Box score |
| 02/03/18 | Evansville, IN (PAC) | Southern Indiana 85, Quincy 53 | Box score |
| 02/01/18 | Evansville, IN (PAC) | Southern Indiana 75, Maryville 50 | Box score |
| 01/27/18 | Lebanon, IL (Statham Center) | Southern Indiana 74, McKendree 62 | Box score |
| 01/25/18 | Evansville, IN (PAC) | Southern Indiana 74, UW-Parkside 57 | Box score |
| 01/20/18 | Evansville, IN (PAC) | Southern Indiana 70, Truman State 50 | Box score |
| 01/18/18 | Evansville, IN (PAC) | Southern Indiana 90, Missouri S&T 71 | Box score |
| 01/15/18 | Louisville, KY (Knights Hall) | Southern Indiana 67, Bellarmine 59 | Box score |
| 01/11/18 | Evansville, IN (PAC) | Southern Indiana 71, Indianapolis 58 | Box score |
| 01/06/18 | Springfield, MO/O'Reilly Event Center | Drury 71, Southern Indiana 55 | Box score |
| 01/04/18 | Evansville, IN (PAC) | Southern Indiana 70, Missouri-St. Louis 65 | Box score |
| 12/31/17 | Evansville, IN (PAC) | Southern Indiana 83, Grace 46 | Box score |
| 12/19/17 | Harrogate, TN | Lincoln Memorial 81, Southern Indiana 73 | Box score |
| 12/16/17 | Evansville, IN (PAC) | Southern Indiana 85, Harris Stowe State 26 | Box score |
| 12/02/17 | Indianapolis, IN (Nicoson Hall) | Southern Indiana 73, Indianapolis 66 | Box score |
| 11/30/17 | Evansville, IN (PAC) | Southern Indiana 67, Lewis 56 | Box score |
| 11/26/17 | Louisville, KY (Knights Hall) | Southern Indiana 59, Northern Michigan 49 | Box score |
| 11/25/17 | Louisville, KY (Knights Hall) | Southern Indiana 53, Grand Valley State 44 | Box score |
| 11/18/17 | Evansville, IN (PAC) | Southern Indiana 77, Wayne State (MI) 54 | Box score |
| 11/16/17 | Evansville, IN (PAC) | Southern Indiana 77, Ohio Dominican 50 | Box score |
| 11/12/17 | Evansville, IN (PAC) | Southern Indiana 86, Saginaw Valley State 60 | Box score |
| 11/10/17 | Evansville, IN (PAC) | Southern Indiana 78, Northwood 39 | Box score |