| Date | Location | Result | |
| May 15, 2021 | St. Charles, Mo. | Illinois Springfield 7, Southern Indiana 1 | Box score |
| May 15, 2021 | St. Charles, Mo. | Southern Indiana 10, Quincy 4 | Box score |
| May 14, 2021 | St. Charles, Mo. | Lindenwood 10, Southern Indiana 2 | Box score |
| May 13, 2021 | St. Charles, Mo. | Southern Indiana 3, Quincy 2 | Box score |
| May 02, 2021 | Evansville, IN | Indianaplolis 7, Southern Indiana 5 | Box score |
| May 01, 2021 | Evansville, IN | Southern Indiana 7, Indianaplolis 5 | Box score |
| May 01, 2021 | Evansville, IN | Indianaplolis 4, Southern Indiana 0 | Box score |
| Apr 30, 2021 | Evansville, IN | Southern Indiana 9, Indianaplolis 3 | Box score |
| Apr 25, 2021 | St. Charles, Mo. | Lindenwood 9, Southern Indiana 3 | Box score |
| Apr 25, 2021 | St. Charles, Mo. | Southern Indiana 9, Lindenwood 4 | Box score |
| Apr 24, 2021 | St. Charles, Mo. | Lindenwood 13, Southern Indiana 2 | Box score |
| Apr 23, 2021 | St. Charles, Mo. | Lindenwood 13, Southern Indiana 2 | Box score |
| Apr 18, 2021 | Evansville, IN | Southern Indiana 8, Lewis 7 | Box score |
| Apr 17, 2021 | Evansville, IN | Southern Indiana 8, Lewis 7 | Box score |
| Apr 17, 2021 | Evansville, IN | Southern Indiana 4, Lewis 3 | Box score |
| Apr 16, 2021 | Evansville, IN | Lewis 8, Southern Indiana 5 | Box score |
| 4/14/2021 | Owensboro, KY | Southern Indiana 6, Kentucky Wesleyan 5 | Box score |
| Apr 11, 2021 | Lebanon, Ill | Southern Indiana 11, McKendree 5 | Box score |
| Apr 11, 2021 | Lebanon, Ill | Southern Indiana 10, McKendree 4 | Box score |
| Apr 09, 2021 | Lebanon, Ill | Southern Indiana 4, McKendree 2 | Box score |
| Apr 09, 2021 | Lebanon, Ill | McKendree 12, Southern Indiana 11 | Box score |
| Apr 07, 2021 | Evansville, IN | Southern Indiana 11, Kentucky Wesleyan 6 | Box score |
| Apr 3, 2021 | Evansville, IN | Southern Indiana 11, Missouri-St. Louis 0 | Box score |
| Apr 2, 2021 | Evansville, IN | Southern Indiana 9, Missouri-St. Louis 0 | Box score |
| Apr 2, 2021 | Evansville, IN | Southern Indiana 9, Missouri-St. Louis 0 | Box score |
| Apr 1, 2021 | Evansville, IN | Southern Indiana 7, Missouri-St. Louis 6 | Box score |
| 3/28/2021 | St. Louis, MO | Southern Indiana 9, Maryville (Mo.) 8 | Box score |
| 3/27/2021 | St. Louis, MO | Southern Indiana 10, Maryville (Mo.) 4 | Box score |
| 3/27/2021 | St. Louis, MO | Southern Indiana 10, Maryville (Mo.) 5 | Box score |
| 3/26/2021 | St. Louis, MO | Maryville (Mo.) 6, Southern Indiana 3 | Box score |
| Mar 21, 2021 | Evansville, IN | Quincy 6, Southern Indiana 5 | Box score |
| Mar 20, 2021 | Evansville, IN | Quincy 4, Southern Indiana 2 | Box score |
| Mar 20, 2021 | Evansville, IN | Southern Indiana 6, Quincy 4 | Box score |
| Mar 19, 2021 | Evansville, IN | Quincy 3, Southern Indiana 2 | Box score |
| 3/14/2021 | Springfield, Ill. | Illinois Springfield 8, Southern Indiana 5 | Box score |
| 3/13/2021 | Springfield, Ill. | Illinois Springfield 7, Southern Indiana 1 | Box score |
| 3/13/2021 | Springfield, Ill. | Illinois Springfield 3, Southern Indiana 1 | Box score |
| 3/12/2021 | Springfield, Ill. | Southern Indiana 4, Illinois Springfield 1 | Box score |
| 3/6/2021 | Nashville, TN | Trevecca Nazarene 8, Southern Indiana 7 | Box score |
| 3/6/2021 | Nashville, TN | Trevecca Nazarene 18, Southern Indiana 1 | Box score |
| 3/5/2021 | Nashville, TN | Trevecca Nazarene 11, Southern Indiana 2 | Box score |
| Feb 27, 2021 | Evansville, IN | Southern Indiana 8, Lake Erie 2 | Box score |
| Feb 27, 2021 | Evansville, IN | Lake Erie 5, Southern Indiana 4 | Box score |
| Feb 26, 2021 | Evansville, IN | Southern Indiana 9, Lake Erie 3 | Box score |